Chemical castration
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Chemical castration is a form of temporary
castration caused by certain
hormonal drugs. It was developed as a temporary preventive measure or punishment, typically for male
child sex offenders and
rapists.
Depo Provera, a
progestin; and
tamoxifen, a drug also used in breast cancer, are the drugs most commonly used today for sex offenders.
Depo Provera acts on the
brain to inhibit hormones that stimulate the
testicles to produce
Testosterone; whereas
Tamoxifen works by blocking the aromatase enzyme.
Depo Provera also neutralises all
testosterone so none can be converted to estrogen by the aromatase enzyme. The herb
chrysin also works by blocking the aromatase enzyme.
Spironolactone, a diuretic, also is an effective testosterone blocker.
Chemical castration also occurs as a natural consequence of
hormone treatment for male-to-female
transsexualism. However, unlike the treatment used on sex offenders, the hormones commonly used lead to permanent
infertility.
[FONT="]Some [/FONT][FONT="]
parasitic[/FONT][FONT="] [/FONT][FONT="]
trematodes[/FONT][FONT="] chemically castrate their host; see [/FONT][FONT="]
microphallus[/FONT]